All 43 US Startups That Raised $100 Million-Plus Series a in 2021

Company name Deal size Company description Series A deal date Valuation Key investors Articulate $1.5 billion Workplace training platform 7/1/2021 $3.75 billion Blackstone, General Atlantic, ICONIQ Capital, LionTree Partners Sierra Space $1.41 billion Dream Chaser commercial space plane 11/19/2021 $4.5 billion AE Industrial Partners, BlackRock Private Equity Partners, Coatue Management, General Atlantic, Moore Strategic Ventures Vaxxinity $1.38 billion Vaccines for neurodegenerative disorders 3/31/2021 $4.37 billion Prime Movers Lab, Tribe Capital Transmit Security $543 million Face detection mobile security system 6/22/2021 $2.74 billion Artisanal Ventures, Citi Ventures, CyberStarts, General Atlantic, Geodesic, Geodesic Capital, Insight Partners, SYN Ventures, The Goldman Sachs Group, Vintage Investment Partners BETA Technologies $425.6 million Electric eVTOL aircraft and recharging pad systems 5/24/2021 $1.46 billion A100x, Amazon.com, Fidelity Management & Research, Hula, RedBird Capital Partners, UP.Partners Neumora $400 million Clinical-stage medicines for brain diseases 10/7/2021 $700 million ARCH Venture Partners, Alexandria Venture Investments, Altitude Life Science Ventures, Catalio Capital Management, Citadel (Hedge Fund), F-Prime Capital, Logos Capital, Mubadala Capital-Ventures, Newpath Partners, Polaris Partners, SoftBank Investment Advisers, The Invus Group, Waycross Ventures, re.Mind Capital Fanatics Trading Cards $350 million Baseball trading cards firm 9/29/2021 $10.4 billion Endeavor, Insight Partners, Silver Lake Calendly $350 million Calendar and scheduling platform 1/26/2021 $3 billion ICONIQ Capital, OpenView Venture Partners Accel Club $170 million Buys and operates Amazon businesses 11/25/2021 N/A Flyer One Ventures, North Wall Capital, RedSeed Ventures Altos Labs $270 million Anti-aging beauty products 9/6/2021 $1.37 billion Jeffrey Bezos, Yuri Milner Highland Electric Transportation $253 million Electric school buses 2/16/2021 $953 million Fontinalis Partners, Vision Ridge Partners Wave $247.6 million Cross-border payments 9/2/2021 $1.7 billion Founders Fund, Partech, Ribbit Capital, Sam Altman, Sequoia Heritage, Stripe Robotic Research $228 million Self-driving software 12/9/2021 N/A Crescent Cove Advisors, Enlightenment Capital, Henry Crown and Company, Luminar, SoftBank Investment Advisers Odyssey Therapeutics $218 million Biotech immunomodulators and oncology drugs 12/7/2021 $300 million Colt Ventures, Creacion Ventures, Foresite Capital Management, HBM Partners, Logos Capital, OrbiMed, SR One Capital Management, Woodline Partners Treeline Biosciences $211.7 million Biotech cancer medicines 4/12/2021 $561.7 million ARCH Venture Partners, Access Industries, Aisling Capital, Ajax Health, Casdin Capital, GV, Kohlberg Kravis Roberts, OrbiMed, T. Rowe Price ProbablyMonsters $200 million Video game studio 9/1/2021 N/A LKCM Headwater Investments Forte $185 million Platform for token-based game economies and NFTs 5/20/2021 $1 billion ACME Capital, Andreessen Horowitz, Battery Ventures, Canaan Partners, Conductive Ventures, Gaingels, Griffin Gaming Partners, Hutt Capital, Intersection Fintech Ventures, Rockaway Blockchain Fund, Samsung NEXT Ventures, Union Grove Venture Partners JOKR $170 million Hyper-local grocery delivery platform 7/20/2021 $1.2 billion Activant Capital, Balderton Capital, Banana Capital, FJ Labs, GGV Capital, Greycroft, HV Capital, Kaszek, Market One Capital, SoftBank Latin America Fund, Tiger Global Management SellersFunding $166.5 million Platform for e-commerce merchants 7/12/2021 N/A Endeavor Catalyst, Fasanara Capital, GAA Investments, Mooring Hitch Investments, Northzone Ventures Landis $165 million Rent-to-own real estate platform 7/27/2021 $182 million Arrive (New York), Dreamers VC, Operator Partners, Sequoia Capital, Signia Venture Partners Acquco $160 million Buys and operates Amazon businesses 5/11/2021 N/A Aman Bhutani, CoVenture, Crossbeam Ventures Partners, FinRebel, Singh Capital Partners Moonshot $160 million Buys and operates Amazon and Shopify businesses 6/15/2021 N/A Ashley Flucas, Asymmetry Ventures, Cathexis Ventures, Evolution VC Partners, FoundersX Ventures, GarageCapital, IOVC, Innova Capital Partners, KSK Angel Fund, Liquid 2 Ventures, Maropost Ventures, N49P, Nate Lipscomb, Outbound Ventures, Sai Ramanan, Siddharth Bajpai, Snapdeal, Victory Park Capital, Y Combinator GentiBio $157 million Autoimmune, allergy biotherapeutics 8/11/2021 $327 million Avidity Partners, Matrix Capital Management, Novartis Venture Fund, OrbiMed, RA Capital Management, Seattle Children’s Hospital, T1D Fund SKIMS $154 million Bodysuits, shapewear and underwear 4/9/2021 $1.6 billion Alliance Consumer Growth, Imaginary Ventures, Thrive Capital Suma Brands $150 million Buys and operates Amazon businesses 8/4/2021 $62.8 million Material Companies, Pace Capital Eikon Therapeutics $148 million Protein interactions drug discovery 5/5/2021 $248 million Foresite Capital Management, Innovation Endeavors, Lux Capital, Resolved Ventures, The Column Group Jasper $134 million Customized credit cards for immigrants and students 7/12/2021 N/A 500 Startups, Benslie International, Clear Future, Gauss Ventures, Off The Grid Ventures, OurCrowd, Saar Wilf, Southern Israel Bridging Fund, Strathmore Group, VU Venture Partners Jeeves $131 million Corporate card software for global startups 6/2/2021 $130.5 million 9Yards Capital, Andreessen Horowitz, BlockFi Ventures, Clocktower Technology Ventures, Daniel Vogel, David Velez, Florian Hagenbuch, FoundersX Ventures, Larry Fitzgerald, Rebel Fund, Ricardo Weder, Sebastian Mejia, Stanford University Venture Fund, Tribe Capital, Uncorrelated Ventures, Urban Innovation Fund, Wollef, Y Combinator Printful $130 million Print product fulfillment company for online retailers 5/24/2021 $1 billion Bregal Sagemount Veho $125 million Crowdsourced e-commerce package delivery service 12/21/2021 $1 billion Bling Capital, Construct Capital (Washington DC), Fontinalis Partners, General Catalyst, Industry Ventures, Origin Ventures EnerVenue $125 million Metal-hydrogen batteries 12/1/2021 N/A IDG Capital, Leland Stanford Junior University, Saudi Aramco Energy Ventures, Schlumberger Capchase $125 million Fintech that pre-pays on recurring revenue receivables 6/4/2021 $175.8 million Bling Capital, Caffeinated Capital, ONEVC, QED Investors, SciFi VC Anthropic $124 million AI safety and research creating large-scale AI systems 5/28/2021 $674 million Center for Emerging Risk Research, Dustin Moskovitz, Eric Schmidt, Jaan Tallinn, James McClave, Metaplanet Holdings D1 Brands $123 million Buys and operates Amazon businesses 8/19/2021 N/A CoVenture, Crossbeam Ventures Partners, ID8 Investments Cellular Biomedicine $120 million Immunotherapies, stem cell therapies for cancers, other diseases 9/29/2021 N/A Government of Singapore Investment Corporation (GIC), Sequoia Capital China, TF Capital, Wuxi AstraZeneca CICC Venture Capital Partnership, Yunfeng Capital Ventyx Biosciences $114 million Biotech drug for inflammatory diseases, autoimmune disorders 3/9/2021 $298 million Cormorant Asset Management, Farallon Capital Management, Janus Henderson Investors, New Science Ventures, OrbiMed, Qiming Venture Partners, RTW Investments, Surveyor Capital, Third Point Ventures, Vivo Capital, Wellington Management, venBio Intrinsic $113 million Buys and operates health and wellness businesses 4/1/2021 N/A Define Ventures, Link Ventures, Mehmet Oz, Redesign Health, Tony Robbins Nomi Health $110 million Healthcare direct payments system 12/8/2021 $1.37 billion Arbor Ventures, Rose Park Advisors Masterworks $110 million Art investing platform 10/5/2021 $1 billion Galaxy Interactive (United States), Left Lane Capital, Tru Arrow Partners Atalanta Therapeutics $110 million RNAi therapeutics for neurodegenerative diseases 1/11/2021 N/A Biogen, F-Prime Capital, Genentech Brave $108 million Developer of privacy web browser 9/1/2021 $508 million All Blue Capital, Quiet Capital HoneyBee $105.6 million Personal finances for employees 9/7/2021 N/A Afore Capital, Baron Davis, Financial Venture Studio, K50 Ventures, Rebalance Capital, Resolute Ventures, ff Venture Capital Chroma Medicine $100.7 million Biotech for genomic medicines 10/12/2021 $255.7 million Atlas Venture, Casdin Capital, Cormorant Asset Management, Janus Capital Management, Newpath Partners, Omega Funds, Osage University Partners, Wellington Management